We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

3 Hazardous Reasons To Steer Clear Of AstraZeneca plc

Royston Wild looks at why AstraZeneca plc (LON: AZN) is an exceptionally risky stock selection.

| More on:

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

shire

Today I am looking at why I believe AstraZeneca (LSE: AZN) (NYSE: AZN.US) is on course to endure lasting earnings weakness.

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Patent problems continue to pummel revenues

AstraZeneca has taken an age to satisfactorily address the problem of patent expiration across many of its critical products, a crushing millstone on group turnover. Indeed, the drugs giant announced earlier this month that the loss of exclusivity on previous earnings drivers — which includes the likes of Seroquel IR, Atacand, Nexium and Merrem — drove revenues 8% lower during 2013 to $25.7bn. This in turn pushed operating profit 54% lower to $3.7bn.

The prospect of further patent troubles has prompted AstraZeneca to warn that it expects “a low-to-mid single digit percentage decline in revenue at constant exchange rates for 2014,” a result which is likely to cause core earnings per share “to decline in the teens.”

Paltry pipeline unlikely to offer near-term respite

AstraZeneca continues to chuck vast amounts of capital into its R&D operations in order to rectify its ailing revenues, and spent $1.43bn on new product development last year, up 8.3% from 2012.

The company is also hoovering up pharma companies across the globe to offset shortfalls in its organic product development. AstraZeneca bought out Bristol-Myers Squibb’s stake in their diabetes-combating joint venture just this month, while other major purchases over the past year include respiratory specialists Pearl Therapeutics and lipids experts Omthera Pharmaceuticals.

Although such measures have helped to boost the pipeline — 11 products entered Phase III trialling last year versus just six in 2012 — the route from laboratory to store shelf is of course a bumpy one which can take many years to complete. Indeed, chief executive Pascal Soriot warned that revenues will only recover to last year’s levels by 2017 as the exclusivity saga rumbles on.

A relatively expensive valuation

Still, investors have been unperturbed by these concerns, and AstraZeneca’s share price has shot almost 15% higher since the middle of January. But in my opinion this leaves the firm at the mercy of a severe price correction, particularly considering the superior strength of its pharmaceutical rivals.

Indeed, AstraZeneca now deals on a P/E rating of 15.6 for 2014, an expensive choice when compared against GlaxoSmithKline which currently trades on a multiple of 15.1 and has a much more bubbly product pipeline and consequently superior earnings prospects.

> Royston does not own shares in any of the companies mentioned in this article. The Motley Fool has recommended shares in GlaxoSmithKline.

More on Investing Articles

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

How much do you need in a Stocks and Shares ISA to generate £100 a day in passive income?

Andrew Mackie looks at what it takes to build a meaningful passive income inside a Stocks and Shares ISA and…

Read more »

Front view of a young couple walking down terraced Street in Whitley Bay in the north-east of England they are heading into the town centre and deciding which shops to go to they are also holding hands and carrying bags over their shoulders.
Investing Articles

How much second income would it take to cover household bills?

Andrew Mackie explores how a Stocks and Shares ISA could be used to generate a second income capable of covering…

Read more »

Young Caucasian man making doubtful face at camera
Investing Articles

This FTSE 100 share pays no dividends. Could that change?

This well-known FTSE 100 share is cash flow positive but does not pay a dividend. Why is that -- and…

Read more »

Two white male workmen working on site at an oil rig
Investing Articles

At almost £6, does the BP share price reflect a new energy future, or just the old oil world?

Mark Hartley examines how geopoliticals are driving the BP share price higher, while its key role in the UK’s energy…

Read more »

Portrait of pensive bearded senior looking on screen of laptop sitting at table with coffee cup.
Growth Shares

This high-risk, high-reward penny stock could be primed to rocket from 0.3p

Jon Smith talks through a mining penny stock that is high risk but could offer a big return if it…

Read more »

Girl buying groceries in the supermarket with her father.
Investing Articles

If you’d put £10,000 into Tesco shares 5 years ago, how much richer would you be now?

Ben McPoland takes a look at how much 4,444 Tesco shares bought half a decade ago would have returned, including…

Read more »

This way, That way, The other way - pointing in different directions
Investing For Beginners

My friend says this is the best cheap share in the market. Is he correct?

Jon Smith mulls a potential cheap share that could offer large returns but is a high-risk option given its recent…

Read more »

Aerial shot showing an aircraft shadow flying over an idyllic beach
Investing Articles

How much would you need to invest in FTSE 100 shares to target a £3,000 annual passive income?

Fancy thousands of pounds a year in passive income paid by blue-chip companies? Our writer explains some ins and outs…

Read more »