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Is this FTSE 100 behemoth a no-brainer AI stock?

Some investors bemoan the lack of AI stocks on the FTSE 100. But one surprising Footsie giant is already making waves with the new tech.

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On the surface, the FTSE 100 is seriously underrepresented when it comes to artificial intelligence stocks. The index is stuffed with ‘dinosaur stocks’ in sectors like oil, tobacco and mining rather than pioneering tech companies at the forefront of AI.

This could be a problem if this exciting technology lives up to the claims of being transformative to our economy and way of life. An investor looking to take advantage of the AI revolution should look elsewhere, right?

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Why large language models?

Not so fast!

While some of the main players in AI are big tech firms like Nvidia, Alphabet or Palantir, the companies that might benefit the most from it might not be the ones producing the chips or the algorithms at all. And because of their lack of direct involvement, the shares could be undervalued today.

There are perhaps a number of stocks that fit the bill here, but the one I’m curious about today is AstraZeneca (LSE: AZN). The £220bn market cap pharma giant has been making headlines already in 2026. The firm recently acquired Boston-based Modella AI whose ‘AI agents’ can be used to help oncology research.

Why can AI help pharmaceuticals companies? Drug discovery is the main advantage. Sifting through vast quantities of data is AI’s forte, and this can help identify potential drug targets. Speedier discovery can help big companies find those ‘blockbuster drugs’ that help millions of patients and bump up the bottom line.

The journey from drug discovery to release is a long one. So the fruits of the introduction of AI might not be felt for five to 10 years. In this vein, CEO Pascal Soriot has set an $80bn target for AstraZeneca’s revenue by 2030. Therefore this is the kind of long-term play that we like to aim for here at The Motley Fool.

Upcoming years

What are the negatives here? Well, it’s an expensive and ruthlessly competitive space. We’ve seen this with the so-called obesity race where drug manufacturers have been clamouring to get appetite-suppressing drugs out to a very hungry market (pun intended).

AstraZeneca is lagging behind Eli Lilly and Novo Nordisk in this area. Although the recent deal with CSPC Pharmaceuticals to use an AI-driven platform to develop weight loss drugs might be another example where artificial intelligence helps the business.

Another potential downside is the valuation. AstraZeneca has proven itself to be one of the bona fide FTSE 100 growth stocks. It’s now (depending on the day) sometimes the largest Footsie company and is trading at 30 times earnings. Pretty expensive for London’s leading index!

To sum up? We’re in the very early stages of artificial intelligence. Over the next decade, we could see some drastic changes in the fortunes of many businesses using the technology. I think AstraZeneca has a real chance of being one of the winners. Maybe not a no-brainer but I’d say it’s worth consideration.

John Fieldsend has positions in AstraZeneca Plc. The Motley Fool UK has recommended AstraZeneca Plc and Novo Nordisk. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

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