We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

This UK share’s outperforming Nvidia. Is it time to buy?

Many UK shares are doing better than America’s most famous tech stock. James Beard looks at one domestic company that’s a global leader in its field.

| More on:
UK supporters with flag

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

With lots of hype surrounding US tech stocks, it’s sometimes easy to overlook UK shares.

For example, since December 2024, there have been dozens of domestic stocks that have performed better than Nvidia. And — since the start of 2025 – the FTSE 100’s gone up by more than the S&P 500. Okay, the differential isn’t very big but the Footsie’s done better. Neither of these facts appear to be widely reported.

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

I suspect some of this can be down to British modesty. Despite having a long history of inventing some amazing things, we tend not to shout about our achievements. Remember, we gave computers, lithium-ion batteries and the internet to the world.

And the London Stock Exchange is home to, in my opinion, some of the most impressive companies on the planet, including pharmaceutical giant AstraZeneca (LSE:AZN).

The UK’s most valuable listed company has a market-cap 94% lower than Nvidia’s, but its share price has performed better over the past 12 months. And AstraZeneca’s latest results suggest it’s on course to reach its target of $80bn of revenue by 2030.

Growing nicely

For the nine months ended 30 September, the group reported an 11% increase in revenue to $43.2bn compared to a year earlier. It also disclosed a 15% rise in core earnings per share. The group’s balance sheet is also improving. At 30 September, its net debt was $2.38bn lower than a year earlier.

During the period, the group announced an “unprecedented” 16 positive Phase III trials. As this is the final step in the approvals process it’s a leading indicator of potential future earnings. Developing new medicines is the biggest challenge AstraZeneca faces. That’s because the exclusivity period it enjoys for new treatments doesn’t last forever. Once this expires, others are free to produce ‘own brand’ alternatives that are often much cheaper.

But the group’s shares aren’t cheap. Having reached a record high in November, they’re currently valued at nearly 30 times forecast earnings for 2025.

Given that its future growth is dependent on reinvesting significant sums in developing new treatments, it might seem a little unfair to criticise the company for its relatively low dividend. However, it has to be acknowledged that a yield of 1.8% is below the FTSE 100 average.

Good news

But AstraZeneca and the UK pharmaceutical industry received a boost last week (1 December) following an announcement that there will be no tariffs on UK exports of medicines to the US. It was also revealed that the NHS has agreed to spend more for innovative drugs and reduce the level of rebate that companies must pay if revenue from the health service exceeds a pre-determined level.

The Association of the British Pharmaceutical Industry has welcomed these developments, which is probably a good indication that the country’s largest listed company will be one of the beneficiaries.

Overall, I think AstraZeneca’s one to consider.

However, it’s just one UK share that’s recently caught my eye. Compared to the US, the stock market on this side of the Atlantic appears cheaper at the moment. And British companies generally pay higher dividends than their international rivals. I think now could be a good time to consider UK stocks.

James Beard has no position in any of the shares mentioned. The Motley Fool UK has recommended AstraZeneca Plc and Nvidia. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Young female couple boarding their plane at the airport to go on holiday.
Investing Articles

Can the Rolls-Royce share price reach £15.97 by the end of August?

The Rolls-Royce share price has had a solid run in the last year. Muhammad Cheema takes a look at whether…

Read more »

Santa Clara offices of NVIDIA
Investing Articles

Up 1,200% in 5 years, here’s why Nvidia could still be a brilliant value stock

An exciting new announcement that could reshape the PC industry has just pushed Nvidia stock... well, just about nowhere really.

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

How investing £4.50 a day could set you on the way to a £1,505 monthly second income

How can UK stocks with high dividend yields help investors earn a meaningful second income from the price of a…

Read more »

Investing Articles

Up 103% with a P/E of 261 — is this FTSE 100 stock still worth buying?

One FTSE 100 stock is quietly moving higher while most investors are still looking elsewhere — is the market missing…

Read more »

Concept of two young professional men looking at a screen in a technological data centre
Investing Articles

The smart money thinks AI stocks look risky — but is there still a chance to buy?

According to fund managers, the AI trade is getting crowded. But they still seem to think it’s the place to…

Read more »

Man putting his card into an ATM machine while his son sits in a stroller beside him.
Investing Articles

Barclays shares are 11% below their 52-week high. Could they be a bit of a bargain to consider?

Overpriced or one of the FTSE 100’s hidden gems? James Beard takes a closer look at how the market is…

Read more »

Stack of one pound coins falling over
Investing Articles

Down 65% but yielding 6.7% – is this beaten-down UK stock now a generational bargain?

Harvey Jones says this UK stock is one of the worst FTSE 100 performers but there are sound reasons to…

Read more »

Portrait of elderly man wearing white denim shirt and glasses looking up with hand on chin. Thoughtful senior entrepreneur, studio shot against grey background.
Investing Articles

Is this FTSE stock really 46% undervalued?

Analysts reckon this FTSE stock should be worth nearly 50% more. James Beard considers why there’s so much positivity surrounding…

Read more »