We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Why GlaxoSmithKline plc Beats AstraZeneca plc And Royal Dutch Shell Plc Beats BP plc For Your Last-Minute ISA

Pharma and oil are great sectors but GlaxoSmithKline plc (LON:GSK) and Royal Dutch Shell Plc (LON:RDSB) are better than AstraZeneca plc (LON:AZN) and BP plc (LON:BP)

| More on:

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

Pharmaceuticals and Big Oil are great sectors for the kind of long-term investment that ISAs are perfect for. It’s generally better to put the tax-wrapper of an ISA around funds that you plan to leave to grow the longest.

Pharma is a good sector because it is both defensive and a play on demographics in the West and East. Fierce opposition to any threatened cuts in the NHS budget demonstrate how protective people are of health services even in times of austerity. A good slug of the money that flows into healthcare ends up in the coffers of the drug companies — in bad times as in good. That’s what makes a defensive investment.

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Demand for drugs will rise and rise. In the West the baby-boomers have become the grey vote, living longer and demanding new treatments to keep them healthy in old age. In emerging markets the rise of a wealthier and more-demanding middle class will fuel spending on healthcare.

The oil sector is out of favour after the precipitous plummet in oil prices. That, for me, is precisely the reason to invest in it now. “I bought Shell (LSE: RDSB) (NYSE: RDS-B.US) when oil was $50″ might not prove to be as big a boast as “I bought Microsoft/Amazon/Google for $1″, but then it’s not such a big risk either. There’s a good chance of mean-reversion, i.e. the operation of market forces, pushing up oil prices eventually. But in any event Big Oil will adapt to the market conditions that prevail over its long-term planning horizons.

Top-down

If you adopt that top-down approach to investing, then the LSE gives you a choice of two big players in each sector. Diversification is a great thing so it can make sense to ride both horses – but for my money there’s a clear winner in each industry.

GlaxoSmithKline (LSE: GSK) has a robust business model, with lower-risk consumer healthcare and vaccines adding ballast to its patent drugs business. GSK’s scale is a big competitive advantage, enabling it to spend heavily on R&D as well as giving it marketing fire-power. The company’s investment in emerging markets should also pay off long-term, despite high-profile stumbles in China.

CEO Pascal Soriot has focused AstraZeneca (LSE: AZN) totally on R&D-led pharma. The company became a biotech play with a dividend attached. Then along came Pfizer’s bid and the share price rocketed. Astra has made significant progress in both its pipeline and its P&L, but the shares have been kept at lofty heights by management’s big promises. My fear is that any disappointment would see the stock punished along with management.

Dividends

Shell has been paying an ever-increasing dividend since 1945, so the 50% drop in oil prices over the past eight months is just a blip in its history. CEO Ben van Beurden has been cutting costs and capital expenditure, a process that could be accelerated if necessary to maintain the cash flow and payout. The US administration is poised to allow Shell to resume drilling in the Alaskan Arctic, which should augur well for its future reserves.

Meanwhile BP (LSE: BP) is still counting the cost of its oil spill in the Gulf of Mexico. The uncertainty of just how many billions of dollars in fines and compensation it will ultimately pay hangs over the company’s valuation. BP is also extraordinarily exposed to Russia: its 20% share in state-owned Rosneft accounts for over half its proven reserves of oil and nearly a quarter of its gas. That’s a double-whammy of risk. BP has a track record of being done over (Sidanko) and having close scrapes (TNK-BP) in Russia. Western sanctions now place the company between a rock and a hard place.

Tony Reading owns shares in GlaxoSmithKline and Shell. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

This way, That way, The other way - pointing in different directions
Investing Articles

Investec vs Aberdeen: which is the better income stock to buy?

Aiming to boost the average yield of his income portfolio, Mark Hartley's looking for new income stocks to buy on…

Read more »

Asian man looking concerned while studying paperwork at his desk in an office
Investing Articles

Down 41% since January, this quality S&P 500 stock is stinking out my ISA

The tide's turned against this S&P 500 robotics stock. Is it time to dump it? Or is there a no-brainer…

Read more »

GSK scientist holding lab syringe
Investing Articles

By mid-2027, analysts expect £6,000 in GSK shares to be worth…

GSK shares are currently trading almost 20% below their 2026 highs. Is there potential for a rebound over the next…

Read more »

Rolls-Royce's Pearl 10X engine series
Investing Articles

Up nearly 1,400% in 5 years! But are Rolls-Royce shares still secretly undervalued?

After skyrocketing, Rolls-Royce shares are now near an all-time high, but could the engineering giant still have more room to…

Read more »

Happy senior couple hugging and enjoying retirement at home
Investing Articles

By mid-2027, analysts expect £5,000 in Barclays shares to be worth…

Barclays shares have outperformed the FTSE 100 by a wide margin over the last year. And City analysts expect to…

Read more »

Man hanging in the balance over a log at seaside in Scotland
Investing Articles

Near 5-year lows, here’s what the experts say about the Diageo share price

Ben McPoland's questioning his sanity after investing in Diageo. Where do institutional analysts see its share price heading over the…

Read more »

British Airways cabin crew with mobile device
Investing Articles

Up 165% but still with a P/E of 7.9. Is the IAG share price a generational bargain?

The IAG share price has been on fire for the last two years, delivering some of the biggest returns in…

Read more »

Emma Raducanu for Vodafone billboard animation at Piccadilly Circus, London
Investing Articles

Here’s the latest Vodafone share price forecasts for 2027

Up 35% in 12 months, the Vodafone share price is beating the stock market right now, but can this momentum…

Read more »