We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

How Much Lower Can AstraZeneca plc Go?

Will AstraZeneca plc’s (LON:AZN) shares continue to fall?

| More on:

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

Right now I’m looking at some of the most popular companies in the FTSE 100 and wider market to try and establish which direction their shares are likely to move.

Today I’m looking at AstraZeneca (LSE: AZN) (NYSE: AZN.US) to ascertain if its share price will continue to fall.

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Going it alone

When AstraZeneca revealed to the City that management was rejecting Pfizer’s increased offer of £55 per share, some shareholders celebrated but most vented their frustration at the decision.

AstraZeneca rejected the bid on the grounds that the takeover would pose a risk to the company’s pharmaceutical work, creating uncertainty for shareholders and workers. Management also stated that the price offered by Pfizer undervalued AstraZeneca as an independent science-led company.

AstraZeneca had previously stated that the minimum price it would be prepared to accept was £59 per share.

Unfortunately, as Pfizer has stated that its offer of £55 per share is “final”, due to City rules, the company cannot raise its offer again, unless there is a material change in circumstances. Pfizer is not allowed to approach with a higher offer for six months.

Short-term pain, long-term gain

AstraZeneca’s shares ended the trading day down 11% yesterday, after the buy-out rejection and it seems as if a lower share price is here to stay.

Indeed, AstraZeneca faces up to three years of shrinking earnings, before the company’s treatment pipeline starts to yield results.

Of course, this has angered many investors, as Pfizer’s offer would have meant that shareholders would have profited in the short term, without having to wait and see if the company can turn things around.  In particular, one top ten shareholder actually went so far as to call management’s rejection of the bid:

“…the single biggest case of value destruction on behalf of shareholders of all time…”

Still, over the long-term AstraZeneca’s gamble could pay off. The company’s management believes that the firm has the potential to grow sales to more than £27bn by 2023, 76% above the level reported for 2013.

This growth is expected to come from several key treatments, with heart drug Brilinta expected to produce sales of £2.1bn by 2023 and diabetes and respiratory medicines adding £4.7bn each.

Nevertheless, these growth forecasts do little to distract shareholders from the fact that AstraZeneca’s sales are not going to hit the level reported for 2013 until 2017 — that’s four years of waiting. 

Unfortunately, with earnings and sales set to fall, now the bid from Pfizer has been rejected, AstraZeneca should trade at a discount to its wider sector. So, as the biotechnology sector currently trades at an average historic P/E of 17 and AstraZeneca currently trades at a forward P/E of 17.1, the company’s current valuation seems about right.

However, AstraZeneca’s forward P/E is forecast to hit 17.2 by 2015, which makes the company look expensive and there is scope for the company’s share price to fall further if it fails to meet self-imposed growth targets. 

Foolish summary

So overall, now that AstraZeneca has rejected Pfizer’s offer, the company’s share price looks like it could fall much further as sales continue to slide. 

Rupert does not own any share mentioned within this article.

More on Investing Articles

ISA coins
Investing Articles

How much would a Stocks and Shares ISA need to replace a £3,064 monthly salary?

Andrew Mackie explores how a Stocks and Shares ISA can power long-term passive income through quality compounders and disciplined investing…

Read more »

Young woman working at modern office. Technical price graph and indicator, red and green candlestick chart and stock trading computer screen background.
Investing Articles

Nvidia’s CEO thinks this company could hit $1trn! Should I add it to my list of stocks to buy?

When hunting for stocks to buy, Mark Hartley is usually wary of US tech hype. But an endorsement like this…

Read more »

Young Caucasian man making doubtful face at camera
Investing Articles

Not sure what a SIPP is? 3 reasons it could pay to know!

Christopher Ruane digs into some of the details of a SIPP and highlights a trio of possible benefits he sees…

Read more »

Investing Articles

Lloyds shares have done nothing for almost half a year — are they stuck at £1?

Mark Hartley takes a closer look at why his Lloyds' shares have barely moved in 2026, but finds reassurance in…

Read more »

Businesswoman calculating finances in an office
Investing Articles

Forget waiting for the IPOs: here’s how to invest in SpaceX and Anthropic today

SpaceX and Anthropic IPOs in 2026 are going to be huge. But investors don’t need to wait for them to…

Read more »

Businessman hand stacking money coins with virtual percentage icons
Investing Articles

2 FTSE investment trusts to consider for passive income in 2026

Ben McPoland spotlights a pair of struggling investment trusts, one of which has crashed 50%. Why does he think they…

Read more »

Tesla car at super charger station
Investing Articles

How much impact could a SpaceX merger have on the Tesla share price?

A SpaceX IPO could be the biggest in history and if Musk's merger plans go ahead, it could save the…

Read more »

A rear view of a female in a bright yellow coat walking along the historic street known as The Shambles in York, UK which is a popular tourist destination in this Yorkshire city.
Investing Articles

£5,000 invested in Greggs shares 2 years ago is now worth…

Greggs' shares have been a diabolical investment over the last two years. But could they offer value today given they’ve…

Read more »