We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

After a string of disasters, is it time to give up on Neil Woodford?

Can Neil Woodford ever come back from the brink?

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

Neil Woodford just can’t catch a break. After several high profile failures in his portfolio last year, the pain has only continued in 2018.

This week, Woodford faced one of his most significant setbacks in history when shares in early-stage biotech firm Prothena collapsed following the failure of a major clinical trial. Woodford has long been a supporter of Prothena, even as the business has faced considerable criticism from other fund managers across the City and Wall Street. 

Should you buy Rolls Royce shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Unfortunately, it now looks as if his belief in the business is misplaced. The shares lost more than two-thirds of their value in just one hour of trading after the disappointing news was announced.

This disaster might have gone unnoticed if it were not for the fact that nearly a fifth of Woodford Patient Capital Trust‘s assets were invested in Prothena (although recently it’s gone down to just 8%). 

A string of failures 

Prothena’s failure follows the collapse of Circassia, which suffered a failure in a cat allergy drug trial in 2016 and Allied Minds, which wrote off $146m worth of investments last year. Together, these two investments alone have cost the Patient Capital trust nearly £50m. The Prothena losses are likely much worse considering the size of the position

Still, following these losses Neil Woodford remains convinced that the portfolio will come good over time. Nearly two-thirds of the portfolio is invested in early-stage biotech businesses working on world-changing breakthroughs. The returns from just one of these start-ups could be enough to erase all losses for good.

But it’s not just at the Patient Capital Trust where Woodford is struggling. The Woodford Equity Income and Income Focus funds are also losing supporters.

Losing fans 

Earlier this month, assets in his flagship Equity Income Fund dropped below £7bn for the first time to £6.6bn, far below the all-time high of £10.2bn although still a sizeable figure. 

Investors have become disappointed by Woodford’s lack of returns since setting out on his own. For the three years to the end of February, his flagship offering returned just 3.9%, compared to the FTSE All-Share index return of 18.8%. High profile company failures, such as Capita and Provident, have weighed on returns, while his preferred investments, which are mainly income stocks, have struggled to win favour with investors.

Time to avoid Woodford?

The former star fund manager faces an uphill battle to rebuild his performance and reputation, but I don’t believe it’s time to give up on his equity income strategy just yet. 

Over the long term, particularly in periods of market volatility, dividend stocks have proven themselves to be the perfect harbours in stormy waters, although in bull markets, performance tends to lag behind the broader market. 

With this being the case, I continue to believe there is a place for Woodford’s equity income offerings in every portfolio. That being said, as I have written before, I am not interested in the Patient Capital trust due to its high-risk nature.

Rupert Hargreaves owns no share mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Arrow symbol glowing amid black arrow symbols on black background.
Investing Articles

By mid-2027, analysts expect $2,913 in Micron stock to be worth

Could investing in Micron stock today be like investing in Nvidia three years ago when it was trading at significantly…

Read more »

Young Asian woman with head in hands at her desk
Investing Articles

£5,000 invested in SpaceX stock after the IPO is now worth…

To the surprise of many, SpaceX stock has fallen below its IPO price of $135 meaning that those who bought…

Read more »

A row of satellite radars at night
Investing Articles

Are BT shares a buy ahead of tomorrow’s Q1 trading update?

Mark Hartley weighs up the investment case for BT shares before its latest update. Will the group surprise investors with…

Read more »

Close-up of a woman holding modern polymer ten, twenty and fifty pound notes.
Investing For Beginners

£2k in this UK stock a year ago would now be worth £7,320

Jon Smith marvels at the performance of a UK stock, but explains why the current momentum means it might not…

Read more »

ISA coins
Investing Articles

How much could £20k invested in a Stocks and Shares ISA grow over time?

Mark Hartley explores the tax-free growth potential of a Stocks and Shares ISA to demonstrate what a £20k investment could…

Read more »

photo of Union Jack flags bunting in local street party
Investing Articles

If you’d put £10k in the FTSE 250 when Keir Starmer became PM, you’d have this now…

Starmer's gone and we have the fifth PM in just four years. But what happened to the FTSE 250 index…

Read more »

Investing Articles

Here’s why Babcock and BAE Systems shares got a Burnham boost today

New PM Andy Burnham has announced his cabinet and defence stocks are rising. But where have I got my money:…

Read more »

Investing Articles

3 under-the-radar UK growth shares that are quietly beating the S&P 500 in 2026

Our writer highlights three British growth shares that have made spectacular gains this year, while everyone was distracted by AI…

Read more »