We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Is this the FTSE 250’s best ‘unicorn’ stock?

The London Stock Exchange isn’t packed to the brim with what some call ‘unicorn’ stocks, but this FTSE 250 biotech firm looks highly interesting.

| More on:

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

The UK is not taking advantage of some very favourable business conditions. This is one of the biggest complaints about the modern state of the country. We have world-leading research hubs, three of the global top 10 universities, and the ability to attract the best talent. And where has it got us? Where are our dominant tech firms? Why aren’t the FTSE 100 and FTSE 250 bursting at the seams with market-disrupting startups? 

Our country’s under-representation in breakout companies makes for valid criticism. But a few do sneak past the challenging investment and regulatory hurdles and acquire that fabled ‘unicorn’ status — reaching $1bn in market cap. One example is exciting biotech firm Oxford Nanopore (LSE: ONT). 

Should you buy Oxford Nanopore Technologies Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Sequencing

So, what does the company do? And is it worth investing in? The name gives much of the game away. Oxford Nanopore was spun out of Oxford University in 2005. The company uses nanopore technology to sequence DNA and RNA. 

Anyone who took GCSE biology knows DNA is a long string of letters (A, T, G, and C). These can be read to derive the properties of living things. 

Well, the nanopore is a handheld device that allows DNA to be sequenced (or read) quickly and easily. This genetic material reading technology has use cases in health and industry. 

Among the many descriptions given in Oxford Nanopore’s investor information, the following quote struck me as an obvious example of where their sequencing devices might come in handy: “What are the differences between these tomato crops? How can we breed better varieties, that are more productive, long lasting or taste better? How can we apply this knowledge to a variety of plants from cereals to flowers?”

A buy?

Sadly, a useful product does not necessarily make a good company (or stock). A quick look at the numbers here tells a revealing story. Oxford Nanpore offered its shares at IPO at 615p. An initial flurry of activity spurred the shares up to a high of 710p before collapsing after that to a low of below a pound. Early investors have watched their holdings drop 66%. 

What happened here? Well, the company has posted losses in every year since IPO and revenue has stagnated too. Without a clear path to profitability or even growing sales, an early-stage growth stock does not look like the most attractive investment to me. 

The most promising outcome from here looks to be a rumoured takeover from a larger US firm (hey, I’ve heard that one before!). This rumour has propelled the shares to double since March. A premium paid in a takeover deal makes for a nice short-term bump, but as a long-term investor I think I’ll be steering clear.

John Fieldsend has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

The Milky Way at night, over Porthgwarra beach in Cornwall
Investing Articles

Is the SpaceX IPO the best growth stock opportunity in a generation?

How about a mix of space exploration, satellite communications, and artificial intelligence? That's what SpaceX stock is all about.

Read more »

Red lorry on M1 motorway in motion near London
Investing Articles

No longer just a grocer: here’s how a shift in strategy could help Tesco shares hit new highs

Mark Hartley looks into the strategic data-driven transition that's helping Tesco become more than just a grocer, and could send…

Read more »

Middle-aged black male working at home desk
Investing Articles

British American Tobacco’s share price slumps 4%! How’s that happened?

British American Tobacco's share price has sunk today, making it the FTSE 100's worst performer. Is it time for dip…

Read more »

A hiker and their dog walking towards the mountain summit of High Spy from Maiden Moor at sunrise
Investing Articles

7.5% yields! Here are 2 very different dividend stocks to consider buying in June

Dividend stocks can be great investments, but they’re not all the same. Stephen Wright outlines two for passive income investors…

Read more »

Person holding magnifying glass over important document, reading the small print
Investing Articles

Takeover talk! But how much is a £10,000 investment in easyJet shares 5 years ago worth today?

How can UK stocks with high dividend yields help investors earn a meaningful second income from the price of a…

Read more »

Middle aged businesswoman using laptop while working from home
Investing Articles

Up 41% in 12 months are Barclays shares still worth buying?

Andrew Mackie explores Barclays shares and argues the market may still be valuing the bank using an outdated playbook, despite…

Read more »

Little girl helping her Grandad plant tomatoes in a greenhouse in his garden.
Investing Articles

Why are ITM Power shares 69% off?

ITM Power shares are among the hottest UK stocks of 2026. So how come the share price is still down…

Read more »

Close-up of British bank notes
Investing Articles

As British American Tobacco shares dip, is this a hot buying opportunity?

Are British American Tobacco shares on their way to completing another decade of dividend growth? Let's check out this latest…

Read more »