We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Why I might buy this soaring stock alongside the Glaxo (GSK) share price

I say GlaxoSmithKline (LON: GSK) is a great investment, but why is this blue-sky biotech making the headlines right now?

| More on:

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

Biotechnology hopefuls come into and go out of fashion from time to time, and the one hitting the headlines at the moment is PureTech Health (LSE: PRTC).

PureTech shares climbed 20% at one point Tuesday, after the share price of Karuna Therapeutics multiplied more than five-fold overnight on the back of a positive clinal trial result. Karuna’s KarXT treatment for schizophrenia is in phase II trials and has reported above-average results, and that’s expected to help clear the way for regulatory approval.

Should you buy PureTech Health Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

PureTech shares responded with their own gain because the company owns 31.6% of Karuna. PureTech’s holding in Karuna is now worth around $580m, up from $130m last week. To me, it doesn’t look as if the PureTech rise fully incorporates the jump in Karuna’s valuation.

Not to be missed?

Analysts appear to agree, and have been wasting no time in reaffirming their buy ratings on the stock – with Liberum Capital and Peel Hunt among those getting in on the bullish optimism.

According to the perfect markets theory, it’s impossible to get ahead of the market because all new information is instantly available to all players and is immediately factored into share prices. In the wider sense, the theory ignores all sorts of factors that drive share prices, but in this case there could well be a short-term anomaly that hasn’t worked its way through yet.

In the short term, we’ll have to see what happens to the PureTech share price over the next few days, but looking at the bigger picture it seems possible that this could be the breakthrough that puts PureTech on the road to profit – current forecasts for further losses make it otherwise very difficult to value.

Safe cash

If I ever did invest in a blue-sky biotech prospect, it would only be a small amount of cash and it would be alongside a bigger investment in an established pharmaceuticals company like GlaxoSmithKline (LSE: GSK) – to sort of balance the overall risk of investing in the medical field.

Glaxo, in fact, is one of those perpetual Buy stocks that I’ve always seen as a great long-term investment, but I’ve never actually got round to picking up any shares.

Over the past five years I’ve missed a fairly modest 24% gain as the company has really only just started back on the road to earnings growth after having to invest heavily to rebuild its drug development pipeline. But that’s still around twice the performance of the FTSE 100, and Glaxo has been paying annual dividends yielding more than 5% for the period.

Still cheap?

Though the share price has appreciated strongly over the past two years, I still reckon we’re looking at very good value with forward price-to-earnings multiples of around 14 being pretty much bang on the Footsie’s long-term average.

Under the leadership of current chief executive Emma Walmsley, the company is well on its way to transforming itself with a long-term plan to separate its pharmaceuticals and consumer businesses, and I think that’s a sound way forward.

To be fair, there’s not much to choose between Glaxo and FTSE 100 rival AstraZeneca, but I think either should provide great long-term rewards.

Alan Oscroft has no position in any of the shares mentioned. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. The Motley Fool UK has recommended AstraZeneca. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Content white businesswoman being congratulated by colleagues at her retirement party
Investing Articles

How investing in a Cash ISA could cost you a comfortable retirement

Cash ISAs are celebrated for the brilliant tax benefits they provide. But could focusing on them cost savers the chance…

Read more »

Young black woman in a wheelchair working online from home
Investing Articles

How much could Barclays shares pay in dividends by 2028?

Barclays is one of the FTSE 100's most popular dividend shares. How much could they provide over the next three…

Read more »

Investor looking at stock graph on a tablet with their finger hovering over the Buy button
Investing Articles

With a 6% yield and a P/E of just 7.4, is this share a screaming buy for a second income?

Mark Hartley looks at the second income potential of a popular UK dividend stock that still looks undervalued despite compelling…

Read more »

Investing Articles

Forget Nvidia! This ETF is booming inside my Stocks and Shares ISA

A thematic ETF inside this writer's ISA has more doubled the return of Nvidia stock so far in 2026. But…

Read more »

Shot of an young mixed-race woman using her cellphone while out cycling through the city
Investing Articles

These cheap FTSE 250 shares could deliver a £1,550 ISA income in just 12 months!

Searching for the best low-cost dividend stocks to buy? Royston Wild reveals two FTSE 250 property shares with yields above…

Read more »

Landlady greets regular at real ale pub
Investing Articles

How much in dividends will these high-yield shares generate in 2026?

With 9.5% and 8.4% dividend yields, what makes these FTSE 100 and FTSE 250 high-yield heroes so special? Royston Wild…

Read more »

British pound data
Investing Articles

£5,000 invested in Nvidia shares when ChatGPT was released is now worth…

The rise of Nvidia shares was kickstarted by the advent of ChatGPT. Our author takes a look at how much…

Read more »

Close-up of children holding a planet at the beach
Investing Articles

Did HSBC just become the FTSE 100’s best dividend stock?

HSBC has long been a strong dividend stock, but could it now be one of the best on the entire…

Read more »