We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Here’s Why AstraZeneca plc And Shire PLC Are Stronger Alone

AstraZeneca plc (LON: AZN) and Shire PLC (LON: SHP) are stronger as independent companies.

| More on:

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

If you were given the choice between receiving £1,000 now, or £2,000 in a years’ time, which would you take?

The answer should be simple, £2,000 in a years’ time would mean a risk-free return of 100% over a 12-month period — a return you’d be hard pressed to find elsewhere. 

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Shareholders of AstraZeneca (LSE: AZN) and Shire (LSE: SHP) have recently been presented with a similar dilemma. Both companies have been subject to bids by larger peers over the past 12 months but over the long term, as standalone companies, the two groups will be able to achieve higher returns for investors.

Rapid growth  

Shire has traditionally been dependent upon treatments for attention deficit hyperactivity disorder but the company is now becoming increasingly focused on rare disease treatment. A small but lucrative market.

Just like Astra, Shire is planning to double annual sales to $10bn by 2020 and if the company achieves this growth, Shire’s shares could surge above the price of £53.19 per share offered for the company. 

Indeed, over the past five years Shires net profit margin has averaged 20%, although City analysts expect the group’s net margin to hit 35% over the next three years. If Shire’s revenue has increased to $10bn by 2020, a net margin of around 35% means that the group will report a net profit of $3.5bn, around £2.3bn. On a per share basis, £3.90 based on the current number of shares in issue.

Over the past 10 years Shire has traded at an average P/E of 20, which indicates that if earnings per share hit £3.90 by 2020, the company’s shares could be worth around £78.00, a 77% gain from present levels. Of course, these figures could change if the company decides buy back stock some of its own shares, a strategy many pharmaceutical companies employ to boost growth.  

Income investment 

It is possible to use the same kind of analysis to arrive at a long-term price target for Astra. The company is targeting sales of $45bn by 2023, based on historic margin figures, on revenue of $45bn the company could report a net profit of $9bn, around £5.6bn. This translates into earnings per share of £4.43.

Based on the fact that many high-growth pharmaceutical companies are currently trading at a P/E of 20, Astra’s shares could hit £88.60 over the next ten years — 88% above current levels. That’s excluding any dividend payments made along the way. Dividends could boost returns by around 4% per year.

And it’s likely that Astra’s payout will grow over time, in line with earnings, which makes the company a perfect candidate for any dividend portfolio.

Rupert Hargreaves has no position in any shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Young female business analyst looking at a graph chart while working from home
Investing Articles

3 UK stocks to consider snapping up if the stock market crashes this month

Harvey Jones picks out three UK stocks that will look even better value if the FTSE 100 has a bad…

Read more »

Investing Articles

1 beaten-down growth stock to consider buying and holding for a decade

After falling 34% in the past 12 months, this growth stock now looks good value and is worthy of consideration,…

Read more »

Close-up image depicting a woman in her 70s taking British bank notes from her colourful leather wallet.
Growth Shares

Turning a £20k ISA into a £12,508 second income

Reinvesting dividends at high yields is one way to earn a second income. But long-term investors should also check out…

Read more »

Black woman using smartphone at home, watching stock charts.
Investing Articles

The Nvidia share price still hasn’t recovered post-earnings. Should I be worried?

Jon Smith explains why the Nvidia share price has traded lower over the past couple of weeks, and offers his…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Just Released: Our Top Value Stock For ISAs In June 2026 [PREMIUM PICKS]

We've just named our top value stock for June 2026 with 31 years of dividend growth under its belt, still…

Read more »

Man hanging in the balance over a log at seaside in Scotland
Investing Articles

The market just sold this FTSE 100 stock. I think it’s focusing on the wrong risk

Andrew Mackie examines whether a recent sell-off has created an opportunity in a FTSE 100 miner for investors worried about…

Read more »

Hand is turning a dice and changes the direction of an arrow symbolizing that the value of an ETF (Exchange Traded Fund) is going up (or vice versa)
Investing Articles

3 top ETFs to consider for a Stocks and Shares ISA in June

A couple of well-chosen ETFs can really boost an ISA portfolio's performance. Here, our writer names a trio that are…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

How to invest £20k in 3 FTSE 100 stocks to get a stunning 7% dividend yield

Harvey Jones picks out some FTSE 100 income stocks that together could deliver a combined yield of more than 7%,…

Read more »