We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Is AstraZeneca plc Overvalued?

AstraZeneca plc (LON: AZN) is one of the most expensive stocks around but is it worth it.

| More on:

You’re reading a free article with opinions that may differ from The Twelfth Magpie’s Premium Investing Services. Become a member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn more, and get a free 'Best Buy Now' stock!.

AstraZeneca (LSE: AZN) (NYSE: AZN.US) is currently one of the most expensive companies in the FTSE 100.

In particular, right now the company trades at a forward P/E of 17.1 compared to the FTSE 100 average of 15. And this is especially surprising when you consider the fact that the company’s earnings are expected to decline by 3% this year and a further 4% next year.

Should you buy AstraZeneca Plc shares today?

Before you decide, please take a moment to review this report first. Despite ongoing uncertainties from US tariffs to global conflicts, Mark Rogers and his team believe many UK shares still trade at substantial discounts, offering savvy investors plenty of potential opportunities to learn about.

That’s why this could be an ideal time to secure this valuable research – Mark’s analysts have scoured the markets to reveal 5 of his favourite long-term ‘Buys’. Please, don’t make any big decisions before seeing them.

Compared to peers Shire and Glaxosmithkline, which trade at forward P/Es of 19 and 15.3 respectively, and are both expected to report earnings growth over the next two years, Astra appears to be overpriced.

Great expectations

However, the City has great expectations for Astra and this seems to be the driving force behind the company’s high valuation. 

You see, after fending off a bid from US pharma giant Pfizer earlier this year, Astra’s management laid out an ambitious growth plan to deliver annual revenues of $45bn by 2023.  That’s a 73% increase in sales from reported revenues of just under $26bn during 2013.

And to back up this ambitious growth target, Astra has developed an industry-leading immuno-oncology portfolio with 13 clinical trials already under way. A further 16 trials are planned and a total of 14 potential new drugs are already in the process of Phase III testing or registration before sale. As many as ten drug approvals are set for 2016.

Analysts at UBS believe that even at current prices, Astra’s pipeline is undervalued. This thesis is based on the fact that the company has eight key assets under development, which have critical milestones in development over the next 18 months. Early stage success of these trails could lead to a re-rating of the company and faster return to growth than many expect.

As if to prove this forecast correct, only a few days after UBS issued its advice, Astra revealed the successful trail of its Brilinta tablets for patients with a history of heart attack. The study, which involved over 21,000 patients, successfully met its primary efficacy endpoint and the treatment led to a significant reduction in major cardiovascular thrombotic events.

The return of Pfizer?

Along with Astra’s impressive treatment pipeline, it seems as if some traders are also betting that Pfizer will return to make another offer for Astra.

Superstar fund manager Neil Woodford estimates that there is a 50:50 chance Pfizer will come back for Astra but, based on Astra’s prospects, he believes that the US giant can “simply cannot afford” a suitable price for Astra. 

Foolish summary 

Overall, Astra’s higher-than-average valuation can be justified by the company’s attractive pipeline of treatments under development and projected revenue growth.  

However, these high expectations leave plenty of room for Astra to disappoint. Only 7% of experimental drugs get from the invention to the production stage, so there’s a high risk Astra could disappoint. 

Rupert Hargreaves has no position in any shares mentioned. The Motley Fool UK has recommended shares in GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

3 beaten-down FTSE 100 shares to consider buying and holding for a decade

Harvey Jones says the real rewards of investing in FTSE 100 shares come over the long term. He thinks these…

Read more »

Three signposts pointing in different directions, with 'Buy' 'Sell' and 'Hold' on
Investing Articles

At 237.8%, the stock market total value-to-GDP ratio is way too high. Here’s what I’m doing.

With the stock market looking more overvalued than at any other time in history, Mark Hartley carefully considers how UK…

Read more »

Chalkboard representation of risk versus reward on a pair of scales
Investing Articles

Greggs shares may look cheap – but they expose a classic investing dilemma!

Greggs shares seem to be going nowhere fast. This shareholder reckons it could be an example of a classic stock…

Read more »

Investing Articles

Here’s how long it could take to go from zero to a £1m Stocks and Shares ISA

Ben McPoland sees this dividend-paying ETF as a solid contender for inclusion in a diversified Stocks and Shares ISA today.

Read more »

Business manager working at a pub doing the accountancy and some paperwork using a laptop computer
Investing Articles

Down 33%, is there a once-in-a-decade chance to buy this quality FTSE 100 stock?

This FTSE 100 stock's been written off as a loser in the age of artificial intelligence. But what if the…

Read more »

The words "what's your plan for retirement" written on chalkboard on pavement somewhere in London
Investing Articles

Britons need a £691,000 pension to retire comfortably. Could FTSE 100 shares be the answer?

FTSE 100 shares can play a valuable role in a retirement saving strategy. But they’re not the only piece of…

Read more »

Abstract 3d arrows with rocket
Investing Articles

Is SpaceX the exception to Warren Buffett’s rule about IPOs?

Warren Buffett is known for his scepticism about IPOs. But every rule has exceptions – and SpaceX isn’t like other…

Read more »

A hiker and their dog walking towards the mountain summit of High Spy from Maiden Moor at sunrise
Investing Articles

How much would you need in a SIPP to replace a £3,000 monthly salary?

Andrew Mackie explores how a SIPP could help build long-term retirement income through disciplined investing and quality dividend stocks.

Read more »